Protease Profiling
We provide analytical services, based on in-house developed and established workflows for mass spectrometry analysis of proteases and their natural substrates:
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Analysis of catalytic and autocatalytic activity
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Determination of cleavage motifs and specific substrate cleavage sites
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Cleavage of natural substrates in vivo
More information
Proteases are key regulatory enzymes, involved in numerous physiological processes from processing of pre-proteins to protein destruction, thus regulating fate, localisation and activity of many proteins. To understand protease specificity and activity we have established workflows for mass spectrometry analysis of (auto)-catalytic activity and the cleavage of natural substrates.
Analyse proteases and their natural substrates
Next level protease analysis using in-house developed LC-MS/MS and bioinformatics workflows.
Individual service
Receive customized solutions, independent of host organism or matrix.
Clear timelines, milestones and detailed reporting.
High sensitivity
Stable, accurate and ultra-sensitive protein analysis with high-end instruments without the need for antibodies.
Support
Our experienced team provides consulting and support at every stage of the project.